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Jörg |
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Eric |
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Merck-Stiftungsprofessur Molecular Biotechnology |
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Helge |
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Volker |
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Beate |
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Molecular Cell Biology of Plants |
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Enrico |
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mRNA-based gene regulation |
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Andreas |
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Plant Cell Physiology |
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Claudia |
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Physiology and Genetics of Lower Eukaryotes |
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Eckhard |
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RNA Regulation in Higher Eukaryotes |
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Michaela |
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RNA Structural Biology |
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Jens |
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Eckhard |
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Prof. | Eric | Helfrich | Natural Product Genomics | |||
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Volker |
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Michaela |
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Enrico |
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Andreas |
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Jörg |
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The talks starts at 17:15
Campus Rieberg, Biocenter, Section of the Building 260 Room 3.13
Tuesday, February 21, 2023
University of Florida, USA
The Natural Products Discovery Center (NPDC) at UF Scripps houses one of the world's largest actinobacterial strain collections, totaling ~125,000 strains. These strains, isolated over the last eight decades and from 69 different countries, encode natural product chemical and biological diversity that are impossible to reproduce in laboratory settings today. We have launched a large-scale genome sequencing campaign to sequence all actinobacterial strains in the collection. The sequenced genomes are curated to create the NPGRC database. Both the strains and the curated genomes have been made available to the scientific community to promote natural products training, research, and associated applications (https://npdc.rc.ufl.edu/home). Lessons learned from our natural products program over the years and preliminary analysis of the strains sequenced to date, benchmarking against the sequenced genomes available in the public databases, will be presented to highlight how such a community resource could radically transform the current paradigm of natural product studies and drug discovery.
Invited by Prof. Helfrich
How to get there:
Institute for Moelcular Bio Science
Campus Riedberg
Biocentre
Building N210-207
Post office box 6
Max-von-Laue-Str. 9
D-60438 Frankfurt
T +49 69 798-29603
F +49 69 798-29600
E info-mbw@bio.uni-frankfurt.de
Managing Director:
Prof. Dr. Jens Wöhnert
Assis. Managing Director:
Prof. Dr. Michaela Müller-McNicoll
Further information: eMail
Dr. Markus Fauth
Tel: 069 798 29603
Dr. Matthias Rose
Tel: 069 798 29529
Secretary: Brunhilde Schönberger
Campus Riedberg
Biozentrum N250 0.05
Max-von-Laue-Straße 9
60438 Frankfurt
Tel: 069 798 29558