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Publikationen 2019

  1. Lippmann C, Ultsch A, and Lötsch J. Computational functional genomics-based reduction of disease-related gene sets to their key components. Bioinformatics 2018 Nov 30. doi: 10.1093/bioinformatics/bty986. [Epub ahead of print]
  2. Weyer-Menkhoff I, and Lötsch J. TRPA1 sensitization produces hyperalgesia to heat but not to cold stimuli in human volunteers. Clin J Pain 2019 Jan 18. doi: 10.1097/AJP.0000000000000677. [Epub ahead of print]
  3. Siebenhofer A, Ulrich LR, Mergenthal K, Berghold A, Pregartner G, Kemperdick B, Schulz-Rothe S, Rauck S, Harder S, Gerlach FM, Petersen JJ. Primary Care Management for Optimized Antithrombotic Treatment [PICANT]: results of a cluster-randomized controlled trial.PLoS One 2019 Jan 9;14(1):e0209366. doi: 10.1371/journal.pone.0209366
  4. Möser CV, Möller M, Fleck SC, Thomas D, Geisslinger G, and Niederberger E. Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice. Neuropharmacology 2019, 146:198-211
  5. Lötsch J, and Hummel T. A machine-learned analysis suggests non-redundant diagnostic information in olfactory subtests. IBRO reports 2019 Jan 7;6:64-73. doi: 10.1016/j.ibror.2019.01.002. eCollection 2019 Jun
  6. Gurke R, Etyemez S, Prvulovic D, Thomas D, Fleck S, Reif A, Geisslinger G, and Lötsch J. A data science-based points at distinct patterns of lipid mediator plasma concentrations in patients with dementia. Frontiers Psychiatry 2019 (accepted)
  7. Sisignano M, Lötsch J, Parnham MJ, and Geisslinger G. Potential biomarkers for persistent and neuropathic pain therapy. Pharmacol Ther 2019 Feb 10. pii: S0163-7258(19)30017-8
  8. Sisignano M, Parnham MJ, and Geisslinger G. Novel approaches to persistent pain therapy. Trends Pharm Sci 2019 Jun;40(6):367-377
  9. Brachtendorf S, El-Hindi K, and Grösch S. Ceramide synthases in cancer therapy and chemoresistance. Prog Lipid Res 2019 Apr 3. pii: S0163-7827(19)30012-8 [Epub ahead of print]
  10. Kurz J, Barthelmes J, Blum L, Ulshöfer T, Wegner MS, Ferreiros N, Roser L, Geisslinger G, Grösch S, Schiffmann S. Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes. Sci Rep 2019 Jan 24;9(1):747
  11. Kringel D, Kaunisto MA, Kalso E, and Lötsch J. Machine-learned analysis of the association of next-generation sequencing based genotypes with persistent pain after breast cancer surgery. Pain 2019 May 15. doi: 10.1097/j.pain.0000000000001616. [Epub ahead of print]
  12. Lötsch J, and Hummel T. Clinical usefulness of self-rated olfactory performance - a data science-based assessment of 6000 patients. Chem Sens 2019 May 11. pii: bjz029. doi: 10.1093/chemse/bjz029. [Epub ahead of print]
  13. Weyer-Menkhoff I, Pinter A, Schlierbach H, Schänzer A, and Lötsch J. Epidermal expression of human TRPM8, but not of TRPA1 ion channels, is associated with sensory responses to local skin cooling. Pain 2019 Jul 22. doi: 10.1097/j.pain.0000000000001660. [Epub ahead of print]
  14. Harder S, Santos SMD, Krozer V, Moll J. Surface Acoustic Wave-Based Microfluidic Coagulation Device for Monitoring Anticoagulant Therapy. Semin Thromb Hemost 2019 Apr;45(3):253-258
  15. Mertens C, Siebenhofer A, Berghold A, Pregartner G, Ulrich LR, Mergenthal K, Kemperdick B, Schulz-Rothe S, Rauck S, Harder S, Gerlach FM, Petersen JJ. Differences in the quality of oral anticoagulation therapy with vitamin K antagonists in German GP practices - results of the cluster-randomized PICANT trial (Primary Care Management for Optimized Antithrombotic Treatment). BMC Health Serv Res 2019 Aug 1;19(1):539
  16. Lötsch J, Geisslinger G, and Walter C. Wissensgenerierung aus komplexen Datensätzen in der humanexperimentellen Schmerzforschung. Der Schmerz 2019 Sep 2. doi: 10.1007/s00482-019-00412-5. [Epub ahead of print]
  17. Martin LM, Möller M, Weiss U, Russe OQ, Scholich K, Pierre S, Geisslinger G, and Niederberger E. 5-Amino-1-beta-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift. Int J Mol Sci 2019, 20(13). pii: E3255. doi: 10.3390/ijms20133255.
  18. Lötsch J, Alfredsson L, and Lampa J. Machine-learning based knowledge discovery in rheumatoid arthritis related registry data to identify predictors of persistent pain. Pain 2019 Aug 30. doi: 10.1097/j.pain.0000000000001693. [Epub ahead of print]
  19. Lötsch J, Ultsch A, and Kalso E. Data-science based subgroup analysis of persistent pain during three years after breast cancer surgery. Eur J Anaesth 2019 (accepted)
  20. Osthues T, and Sisignano M. Oxidized lipids in persistent pain states. Frontiers Pharmacol 2019 (accepted)
  21. Lötsch J, and Hummel T. A data science-based analysis of seasonal patterns in outpatient presentations due to olfactory dysfunction. Rhinology 2019 (accepted)
  22. Lötsch J, and Hummel T. Machine-learned analysis of side-differences in odor identification performance. Neuroscience 2019 Nov 2. pii: S0306-4522(19)30678-5. doi: 10.1016/j.neuroscience.2019.09.033. [Epub ahead of print]
  23. Lötsch J, Walter C, Zunftmeister M, Zinn S, Wolters M, Ferreiros N, Rossmanith T, Oertel BG, and Geisslinger G. A data science approach to the selection of most informative readouts of the human intradermal capsaicin pain model to assess pregabalin effects. Basic Clin Pharmacol Toxicol 2019 Oct 14. doi: 10.1111/bcpt.13337. [Epub ahead of print]
  24. Kringel D, Kaunisto MA, Kalso E, and Lötsch J. Machine-learned analysis of global and glial/opioid intersection related DNA methylation in patients with persistent pain after breast cancer surgery. Clin Epigenetics 2019 (accepted)
  25. Niederberger E, Parnham MJ, Maas J, and Geisslinger G. 4Ds in health research—working together toward rapid precision medicine. EMBO Mol Med 2019, doi: 10.15252/emmm.201910917. [Epub ahead of print]
  26. Lötsch J, Hähner A, and Hummel T. Machine-learning-derived rules set excludes risk of Parkinson’s disease in patients with olfactory or gustatory symptoms with high accuracy. J Neurol 2019 Nov 1. doi: 10.1007/s00415-019-09604-6. [Epub ahead of print]
  27. Walter C, Oertel BG, Felden L, Nöth U, Deichmann R, and Lötsch J. Delta-9-tetrahydrocannabinol reduces the performance in sensory delayed discrimination tasks. A pharmacological-fMRI study in healthy volunteers. IBRO Reports 2019 (accepted)