SFB 1177

Dear prospective candidate for our Master scholarships.

Before you take a closer look at the website of the research centre, we would like to give you some basic information about it.   

Here is a short profile for your convenience:  
Autophagy is a highly conserved catabolic process that serves as quality control mechanism in cells by selectively removing damaged and superfluous organelles or other harmful cytosolic material, such as aggregated proteins or invaded bacteria. Under stress or energy restriction autophagy provides recycled building blocks for the synthesis of new cellular components. Autophagy plays a vital role in protecting against disease, but in recent years it became clear that the effect of autophagy is highly contextual. While it acts for instance as an anti-tumorigenic mechanism in healthy cells, cancer cells exploit the cytoprotective effect of autophagy to overcome stress conditions and nutrient limitation caused by rapid tumor growth. SFB 1177 aims at gaining a more detailed insight into the mechanistic details of autophagic pathways to better understand its role in disease development and eventually exploit this knowledge therapeutically. The SFB employs a variety of techniques ranging from structural biology to biochemistry and cell biology. The availability of several model organisms (M. musculus, C. elegans, P. anserine, access to clinical models and a proteomics facility complement the variety of state-of-the-art methods employed by the SFB.

If you could imagine collaborating with and becoming part of this research group during your Master Program at Goethe University and apply for the Master scholarship, click here for more detailed information:  website.

If you contact the research group please write “Goethe Goes Global - Master scholarships” in the reference line of your e-mail.

Contact (ONLY for specific questions regarding the research unit):

Dr. Heide Genau, genau@med.uni-frankfurt.de