Manuela Nowotny

Nowotny

Lecturer (Akademische Rätin)

Email:
Phone:

nowotny@bio.uni-frankfurt.de
+49 69 / 798 42063

Recent Projects and Research Interests:

Insect hearing
In this project I investigate together with Manfred Kössl the signal transduction in a high frequency hearing insect, the bushcricket Mecopoda elongata. With Laser-Doppler-Vibrometer measurements and physiological records we study the mechano-electrical transduction in the hearing organ, called Crista acustica.

Staff:
Arun Palghat Udayashankar and Jennifer Hummel

Funding:
Deutsche Forschungsgemeinschaft (NO 841/1-1)
"Nachwuchswissenschaftler/innen im Fokus" Goethe Universität

Recent Publications:
Hummel, J.; Kössl, M.;
Nowotny, M. (2011)
“Sound-induced tympanal membrane motion in bushcrickets and its
relation to the sensory output” J Ex Bio, accepted
Nowotny, M.; Hummel, J.; Weber, M.; Möckel, D.; Kössl, M. (2010)
“Acoustic-induced motion of the bushcricket (Mecopoda elongata, Tettigoniidae) tympanum.” J Comp Physiol A 196: 939-945.



Tinnitus

In this project I investigate together with Bernhard Gaese and Manfred Kössl the startle reflex response in gerbils. The aim of the project is the identification of gerbils with induced tinnitus.

Staff:
Lenneke Kiefer

Funding:
Adolf-Messer Stiftungspreis 2009

Recent Publication:
Nowotny, M.; Remus M.; Kössl, M.; Gaese, B.H. (2011)
"Characterization of the Perceived Sound of Trauma-Induced Tinnitus in Gerbils"; JASA, accepted


Awards:

Attempto Award 2007

The Attempto Award has been presented to young researchers for excellent work in the field of neurobiology.

Adolf Messer-Stiftungspreis 2009

The Award of the Adolf Messer-Foundation is given for foward-looking projects of basic research in natural and medical science.


Publications

2012 --- 2011 --- 2010 --- 2009 --- 2006 --- 2003 --- 2000

2012

Palghat Udayashankar A.; Kössl M.; Nowotny M. (2012). In-vivo measurements of tonotopically ordered traveling waves. PLoS One. 7(2): e31008.

Möckel, D.Lang, J.Kössl, M. Nowotny, M. (2012). Temperature-dependence of DPOAEs in tympanal organs. J Exp Biol accepted.

2011

Nowotny M.; Remus M.; Kössl M.; Gaese B.H. (2011). Characterization of the Perceived Sound of Trauma-Induced Tinnitus in Gerbils. J Acoust Soc Am 130(5): 2827-2834.

Hummel J.; Kössl M.; Nowotny M. (2011). Sound-induced tympanal membrane motion in bushcrickets and its relation to the sensory output. J Exp Biol 214: 3596-3604.

Nowotny M.; Gummer A.W. (2011). Vibration responses of the organ of Corti and the tectorial membrane to electrical stimulation. J. Acoust. Soc. Am. Volume 130: 3852-3872.

Palghat Udayashankar A.; Kössl M.; Nowotny M. (2011). Tonotopically ordered traveling waves in the hearing organs of bushcrickets in-vivo. In: Mechanics of Hearing. Shera C. and Olson E. (Eds.). World Scientific, Singapore, New Jersey, London, Hong Kong, pp. 466-472.

Nowotny M.; Weber M.; Palghat Udayashankar A.; Hummel J.; Kössl M. (2011). Sound Transduction in the Auditory System of Bushcrickets. In: Mechanics of Hearing. Shera C. and Olson E. (Eds.). World Scientific, Singapore, New Jersey, London, Hong Kong, pp. 461-465.

Fleischer M.; Harasztosi C.; Nowotny M.; Zahnert T.; Gummer A.W. (2011). Continuum Mechanical Model of the Outer Hair Cell. In: Mechanics of Hearing. Shera C. and Olson E. (Eds.). World Scientific, Singapore, New Jersey, London, Hong Kong, pp. 160-165.
2010

Nowotny, M.; Hummel, J.Weber, M.Möckel, D.Kössl, M. (2010). Acoustic-induced motion of the bushcricket (Mecopoda elongata, Tettigoniidae) tympanum. J Comp Physiol A 196: 939-945.

2009

Gaese, B. H. ; Nowotny, M. ; Pilz, P. K. D. (2009). Acoustic startle and prepulse inhibition in the Mongolian gerbil. Physiology & Behavior 98: 460-466.

2006

Nowotny, M.; Gummer, A.W. (2006). Nanomechanics of the subtectorial space caused by electromechanics of cochlear outer hair cells. Proc Natl Acad Sci USA 103: 2120-2125.

Nowotny, M.; Gummer, A.W. (2006). Elektromechanische Transduktion: Einfluss der äußeren Haarsinneszellen auf das Bewegungsmuster des Corti-Organs. HNO 54: 536-543.

Gummer, A. W.; Nowotny, M.; Scherer, M. P.; Vete?ník, A. (2006). Pulsating fluid motion and deflecting of the stereocilia of the inner hair cells due to the electromechanics of the outer hair cells. In: Nuttall, A.. L.; Ren, T.; Gillespie, P.; Grosh, K.; de Boer, E. (Hrsg.): Auditory Mechanisms: Processes and Models. World Scientific, New Jersey, London, Singapore, Hong Kong, pp. 101?102.

Nowotny, M.; Gummer, A. W. (2006). What do the OHCs move with their electromotility? In: Nuttall, A. L.; Ren, T.; Gillespie, P.; Grosh, K.; de Boer, E. (Hrsg.): Auditory Mechanisms: Processes and Models. World Scientific, New Jersey, London, Singapore, Hong Kong, pp. 17?25.
2003

Scherer, M. P.; Nowotny, M.; Dalhoff, E.; Zenner, H. P.; Gummer, A. W. (2003). High-frequency vibration of the organ of Corti in vitro.
In: Gummer, A. W. (Hrsg.): Biophysics of the Cochlea: from Molecules to Models. World Scientific, New Jersey, London, Singapore, Hong Kong, pp. 271-277.

2000 Martin T.; Nowotny M. (2000). The docodont Haldanodon from the Guimarota mine.- In: Martin T & Krebs B (eds.) Guimarota , a Jurassic Ecosystem. Pfeil Verlag. München.

 Abstracts

2011 --- 2010 --- 2009 --- 2008 --- 2006 --- 2005 --- 2004 --- 2003 --- 2002 --- 2001

2011

Nowotny M., Remus M., Kössl M., Gaese B. 2011.Trauma-induced tinnitus in gerbils centers around the induction frequency. In: Santi PA (ed.) Abstracts of the 34th Annual Midwinter Research Meeting., Association for Research in Otolaryngology.# 188

Hummel J., Kössl M., Nowotny M. 2011. Does the auditory nerve activity reflect the tympanal membrane motion in bushcrickets? 8th Göttingen Meeting of the German Neuroscience Society. # T17-8A.

Lang J., Kössl M., Nowotny M. 2011. Temperature dependence of DPOAEs in grasshoppers. 8th Göttingen Meeting of the German Neuroscience Society. # T17-2C.

Hummel, J., Kössl, M. und Nowotny, M. (2011). Functional coupling of tympanal membrane motion and tympanal nerve response. ?Invertebrate Sound and Vibration, 13th International Meeting?.

Remus M., Gaese B., Kössl M., Nowotny M. 2011. Trauma-induced tinnitus in gerbils centers around the induction frequency. 8th Göttingen Meeting of the German Neuroscience Society. # T17-8C.

Udajashankar A.P., Kössl M., Nowotny M. 2011. Auditory mechanics of bushcrickets in-vivo. 8th Göttingen Meeting of the German Neuroscience Society. # T17-4A.

Nowotny, M., Palghat Udayashankar, A., Weber, M., Hummel, J. und Kössl, M. (2011). Sound Transduction in the Auditory System of Bushcrickets.?Mechanics of Hearing 2011, The 11th International
2010

Fleischer, M.; Zahnert, T.; Harasztosi, C.; Nowotny, M.; Baumgart, J.; Gummer, A.W. (2010). ?OHC Somatic Electromechanical Force Coupled Directly to the IHC Stereocilia. Assoc Res Otolaryngol Abs: 670.

Martin, T.; Nowotny, M.; Fischer, M. (2010). New data on tooth replacement in the Late Jurassic docodont mammal Haldanodon expectatus. 70th Anniversary Meeting Society of Vertebrate Paleontology, Program and Abs: 130A

2009

Nowotny, M. ; Möckel, D. ; Weber, M. ; Kössl, M. (2009). ?Sound induced vibration pattern on the tympanal membranes of the bushcricket Mecopoda elongata.? 8th Göttingen Meeting of the German Neuroscience Society: T17-1C.

Gaese, B. ; Nowotny, M. ; Pilz, P. K. D. (2009). ?Acoustic startle response in the wild-type and domesticated Mongolian gerbil? 8th Göttingen Meeting of the German Neuroscience Society: T18-6B.

Gummer, A.W. ; Chiaradia, C. ; Nowotny, M. (2009). OHC Somatic Electromechanical Force Coupled Directly to the IHC Stereocilia.
Assoc Res Otolaryngol Abs: 256.

Chiaradia C. ; Nowotny, M. ; Gummer A.W. (2009). OHC induced vibration pattern of the basilar membrane. In: Cooper, N.P. and Kemp, D.T. (Eds.): Concepts and Challenges in the Biophysics of Hearing. World Scientific, Singapore, New Jersey, London, Hong Kong: 283-287.

2008

Chiaradia, C.; Nowotny, M.; Gummer, A. W. (2008): Deflection of IHC Stereocilia by OHC Somatic Electromotility.
Assoc Res Otolaryngol Abs: 176.

Eckrich, T.; Nowotny, M.; Harasztosi, C.; Scherer, M.; Gummer, A. W. (2008): Impedance Measurements of Isolated Outer Hair Cells. Assoc Res Otolaryngol Abs: 179.

2006

Nowotny, M.; Gummer, A. W. (2006). Influence of electrically-induced mobility of outer hair cells on the organ of Corti motion. Assoc Res Otolaryngol Abs: 997.

2005

Nowotny, M.; Gummer, A. W. (2005). Outer hair cell induced motion of the organ of Corti: Mechanisms of active amplification.

In: Elsner, N. ; Zimmermann, H. (Hrsg.): The Neurosciences from Basic Research to Therapy. Proceedings of the 30th Göttingen Neurobiology Conference 2005. Stuttgart, Georg Thieme: 98.

Nowotny, M.; Gummer, A. W. (2005). Influence of electrically-induced somatic mobility of outer hair cells on the basilar membrane motion. Assoc Res Otolaryngol Abs: 328.

Nowotny, M.; Gummer, A. W. (2005). OHC-induced motion of the organ of Corti. Abstract book of the 42nd Workshop on Inner Ear Biology: O11.

2004

Nowotny, M.; Zenner, H.-P.; Gummer, A. W. (2004). Impact of outer hair cell electromotility on organ of Corti vibration ? results from an in situ preparation. Assoc Res Otolaryngol Abs: 1002.

2003

Nowotny, M.; Zenner, H.-P.; Gummer, A. W. (2003). The motion of the subtectorial space and its resulting fluid motion in the guinea pig cochlea. In: Elsner, N.; Zimmermann, H. (Hrsg.): The Neurosciences from Basic Research to Therapy. Proceedings of the 29th Göttingen Neurobiology Conference 2003. Stuttgart, Georg Thieme: 328.

Nowotny, M.; Scherer, M. P.; Zenner, H.-P.; Gummer, A. W. (2003). Stimulus induced volume change in the subtectorial space of the organ of Corti. Assoc Res Otolaryngol Abs: 112.

Nowotny, M.; Zenner, H.-P.; Gummer, A. W. (2003). Electrically induced motion of the organ of Corti in the guinea-pig cochlea and its possible effect on the response of inner hair cells. Abs 96. Jahrestagung der Deutschen Zoologischen Gesellschaft: P5.

Gummer, A. W.; Nowotny, M.; Scherer, M. P.; Zenner, H.-P.(2003). Laserinterferometrische Untersuchung des subtectorialen Spaltes der Säugetiercochlea. HNO 28: 147.

2002

Gummer, A. W.; Scherer, M. P.; Nowotny, M. (2002). Coupling of electromechanical force into the organ of Corti. Assoc Res Otolaryngol Abs: 720.

Scherer, M. P.; Nowotny, M.; Gummer, A. W. (2002). High frequency vibration modes in the organ of Corti. Assoc Res Otolaryngol Abs: 911.

2001

Nowotny, M.; Martin, T.; Fischer, M. (2001). Dental anatomy and tooth replacement of Haldanodon exspectatus (Docodonta, Mammalia) from the Upper Jura of Portugal. Journal of Morphology 248, 3: 268.

 

Nonscientific output

2007